DBCO-PEG5-GGG-NH2
Based on 1 Customer Validation
DBCO-PEG5-GGG-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.55%
- CAS No.: 2762519-06-0
- Formula: C37H50N6O10
- Molecular Weight:738.84
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E1122 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2762519-06-0
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Appearance Solid
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Molecular Weight 738.84
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Formula C37H50N6O10
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Color White to light yellow
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SMILES
O=C(NCC(=O)NCC(=O)NCCOCCOCCOCCOCCOCCNC(=O)CCC(=O)N1C=2C=CC=CC2C#CC=3C=CC=CC3C1)CN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (67.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3535 mL | 6.7674 mL | 13.5347 mL | 33.8368 mL |
| 5 mM | 0.2707 mL | 1.3535 mL | 2.7069 mL | 6.7674 mL | |
| 10 mM | 0.1353 mL | 0.6767 mL | 1.3535 mL | 3.3837 mL | |
| 15 mM | 0.0902 mL | 0.4512 mL | 0.9023 mL | 2.2558 mL | |
| 20 mM | 0.0677 mL | 0.3384 mL | 0.6767 mL | 1.6918 mL | |
| 25 mM | 0.0541 mL | 0.2707 mL | 0.5414 mL | 1.3535 mL | |
| 30 mM | 0.0451 mL | 0.2256 mL | 0.4512 mL | 1.1279 mL | |
| 40 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8459 mL | |
| 50 mM | 0.0271 mL | 0.1353 mL | 0.2707 mL | 0.6767 mL | |
| 60 mM | 0.0226 mL | 0.1128 mL | 0.2256 mL | 0.5639 mL |
DBCO-PEG5-GGG-NH2 Related Classifications
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