DC432
HCT116 is a peptidomimetic inhibitor of N-terminal methyltransferase 1/2 (NTMT1/2) with an IC50 of 54 nM. HCT116 can inhibit the N-terminal methylation level of NTMT1/2 substrates in HCT116 cells, and is used for the study of NTMT1/2 probes.
For research use only. We do not sell to patients.
- CAS No.: 2388988-70-1
- Formula: C55H100N28O10
- Molecular Weight:1313.56
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 54 nM (NTMT1/2)[1].
Chemical Information
-
CAS No. 2388988-70-1
-
Molecular Weight 1313.56
-
Formula C55H100N28O10
-
Sequence
{p-Hydroxybenzeneacetic acid}-Pro-Lys-Arg-Arg-Arg-Arg-Arg-Arg-NH2
-
Sequence Shortening
{p-Hydroxybenzeneacetic acid}-PKRRRRRR-NH2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DC432 Related Classifications
HY-P10028 Related Classifications
Powered by Bioz