Elcatonin
Based on 1 Customer Validation
Elcatonin (Carbocalcitonin) is a synthetic analog of eel calcitonin. Elcatonin increases bone mineral density, inhibits bone resorption and processes a central analgesic effect.
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- CAS. Nr.: 60731-46-6
- Formel: C148H244N42O47
- Molecular Weight:3363.77
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1]
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Dosage:20 U/kg
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Administration:Subcutaneously; 2 d after oxaliplatin administration
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Result:Attenuated oxaliplatin-induced cold in rtas.
Chemical Information
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CAS. Nr. 60731-46-6
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Molecular Weight 3363.77
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Formel C148H244N42O47
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Synonyms
Carbocalcitonin
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Sequence
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Lactam bridge: Ser1-Asu6)
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Sequence Shortening
SNLST{Asu}VLGKLSQELHKLQTYPRTDVGAGTP-NH2 (Lactam bridge: Ser1-Asu6)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (29.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
Verweise
[1]. Knopp JA, et al. Calcitonin for treating acute pain of osteoporotic vertebral compression fractures: a systematic review of randomized, controlled trials. Osteoporos Int. 2005;16(10):1281‐1290. [Content Brief]
[2]. Aoki M,et al. Comparison of the effects of single doses of elcatonin and pregabalin on oxaliplatin-induced cold and mechanical allodynia in rats. Biol Pharm Bull. 2014;37(2):322‐326. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.2973 mL | 1.4864 mL | 2.9729 mL | 7.4321 mL |
| 5 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.4864 mL | |
| 10 mM | 0.0297 mL | 0.1486 mL | 0.2973 mL | 0.7432 mL | |
| 15 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4955 mL | |
| 20 mM | 0.0149 mL | 0.0743 mL | 0.1486 mL | 0.3716 mL | |
| 25 mM | 0.0119 mL | 0.0595 mL | 0.1189 mL | 0.2973 mL |
Elcatonin Related Classifications
HY-P0007 Related Classifications
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