TOPS
Based on 1 publication(s) in Google Scholar
TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H2O2 and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 40567-80-4
- Formula: C12H18NNaO3S
- Molecular Weight:279.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) TOPS
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Biological Activity
TOPS (3.2 mM) reacts with 4-AAP in the presence of H2O2 and nanocrystalline cobalt selenide to produce a purple product with a maximum absorbance at 550 nm[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 40567-80-4
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Appearance Solid
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Molecular Weight 279.33
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Formula C12H18NNaO3S
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Color White to off-white
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SMILES
O=S(CCCN(CC)C1=CC=CC(C)=C1)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Redox Biol
USP20 governs tyrosine kinase inhibitors resistance through ferroptosis evasion by targeting GPX4 in cancers. [Abstract]2026 May:92:104086. PMID: 41844497
Solvent & Solubility
DMSO : 100 mg/mL (358.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5800 mL | 17.9000 mL | 35.8000 mL | 89.4999 mL |
| 5 mM | 0.7160 mL | 3.5800 mL | 7.1600 mL | 17.9000 mL | |
| 10 mM | 0.3580 mL | 1.7900 mL | 3.5800 mL | 8.9500 mL | |
| 15 mM | 0.2387 mL | 1.1933 mL | 2.3867 mL | 5.9667 mL | |
| 20 mM | 0.1790 mL | 0.8950 mL | 1.7900 mL | 4.4750 mL | |
| 25 mM | 0.1432 mL | 0.7160 mL | 1.4320 mL | 3.5800 mL | |
| 30 mM | 0.1193 mL | 0.5967 mL | 1.1933 mL | 2.9833 mL | |
| 40 mM | 0.0895 mL | 0.4475 mL | 0.8950 mL | 2.2375 mL | |
| 50 mM | 0.0716 mL | 0.3580 mL | 0.7160 mL | 1.7900 mL | |
| 60 mM | 0.0597 mL | 0.2983 mL | 0.5967 mL | 1.4917 mL | |
| 80 mM | 0.0447 mL | 0.2237 mL | 0.4475 mL | 1.1187 mL | |
| 100 mM | 0.0358 mL | 0.1790 mL | 0.3580 mL | 0.8950 mL |
TOPS Related Classifications
HY-15933 Related Classifications
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