MAGEH1 - MAGE family member H1 Gene

Also Known as APR1; APR-1; MAGEH

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 28986

About MAGEH1

Cytogenetic location: Xp11.21 Genomic coordinates (GRCh38): X:55,452,127-55,453,566 (from NCBI)

This gene has 1 transcript (splice variant), 170 orthologues and 37 paralogues.

Summary

This gene belongs to the non-CT (non Cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with Apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]

MAGEH1 Products (1)

mRNA Protein Name
NM_014061.5 NP_054780.2 melanoma-associated antigen H1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAGEH1 Protein Structure

MAGE

MAGE: MAGE family (60 - 176)

  • 0
  • 100
  • 200
  • 219 a.a.
Protein Preferred Names Protein Names

melanoma-associated antigen H1

  • apoptosis-related protein 1

MAGEH1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MAGEH1 Q9H213 SH2B2 Homo sapiens O14492-2
Y2H Array
32296183
Intra
MAGEH1 Q9H213 SH2B2 Homo sapiens O14492-2
Y2H Prey Pooling
32296183
Intra
MAGEH1 Q9H213 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
25416956
Intra
MAGEH1 Q9H213 HMBOX1 Homo sapiens Q6NT76
Y2H Array
25416956
Intra
MAGEH1 Q9H213 TNIP1 Homo sapiens Q15025
Validated Y2H
25416956
Intra
MAGEH1 Q9H213 TNIP1 Homo sapiens Q15025
Y2H Array
25416956
Intra
MAGEH1 Q9H213 TNIP1 Homo sapiens Q15025
Y2H Prey Pooling
25416956
Intra
MAGEH1 Q9H213 YWHAG Homo sapiens P61981
Y2H Array
32814053
Intra
MAGEH1 Q9H213 YWHAG Homo sapiens P61981
Validated Y2H
32814053
Intra
MAGEH1 Q9H213 YWHAG Homo sapiens P61981
Y2H Pooling
32814053
Intra
MAGEH1 Q9H213 TRIM41 Homo sapiens Q8WV44
Validated Y2H
25416956
Intra
MAGEH1 Q9H213 TRIM41 Homo sapiens Q8WV44
Y2H Prey Pooling
25416956
Intra
MAGEH1 Q9H213 ZSCAN9 Homo sapiens O15535
Y2H Array
25416956
Intra
MAGEH1 Q9H213 SETDB1 Homo sapiens Q15047-2
Y2H Array
32814053
Intra
MAGEH1 Q9H213 SETDB1 Homo sapiens Q15047-2
Y2H Pooling
32814053
Intra
MAGEH1 Q9H213 SETDB1 Homo sapiens Q15047-2
Validated Y2H
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Necatoriasis

  • Miner'S Anaemia

  • Negro Cachexia

  • Dochmiasis

  • Ground Itch Disease

  • Brickmaker'S Chlorosis

  • Coolie Itch Anaemia

  • Cachexia Aquosa

  • Dew Itch Anaemia

  • Brickmaker'S Anaemia

  • Tunnel Worker'S Anaemia

  • Egyptian Anaemia

  • Tunnel Worker'S Disease

  • Miner'S Cachexia

  • Greisinger Disease

  • Tropical Chlorosis

  • Egyptian Chlorosis

  • Tunnel Anaemia

  • Dochmiosis

  • Necatorosis

  • African Cachexia

  • Water Itch Anaemia

  • Infection Due To Necator Americanus

  • St Gotthard Disease

  • Gotthard Tunnel Disease
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Ostertagiasis
Ascaris Lumbricoides Infection

  • Ascariasis

  • Ascaris Lumbricoides Infection, Susceptibility To

  • Ascariasis, Susceptibility To

  • Ascariasis - Roundworm

  • Infection Due To Ascaris Lumbricoides

  • Ascaridiasis

  • Roundworm Infection

  • Ascaridia

  • Ascaridiosis

  • Ascaridosis

  • Ascariosis

  • Ascaris

  • Ascaris Lumbricoides Infestation

  • Ascaris Infection

  • Infection By Ascaridia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07979 MAGEH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MAGEH1 VGNC VGNC:42926
Bos taurus MAGEH1 VGNC VGNC:31145
Mus musculus MAGEH1 MGD MGI:1922875
Rattus norvegicus MAGEH1 RGD RGD:1359316
Others MAGEH1 NCBI