ONECUT3 - one cut homeobox 3 Gene

Also Known as OC3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 390874

About ONECUT3

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,753,506-1,780,988 (from NCBI)

This gene has 1 transcript (splice variant), 224 orthologues and 2 paralogues. Biased expression in stomach (RPKM 1.8) and duodenum (RPKM 0.1).

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ONECUT3 Products (1)

mRNA Protein Name
NM_001080488.2 NP_001073957.1 one cut domain family member 3

ONECUT3 Protein Structure

CUT

CUT: CUT domain (317 - 394)

Homeobox

Homeobox: Homeobox domain (415 - 468)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 494 a.a.
Protein Preferred Names Protein Names

one cut domain family member 3

  • OC-3

ONECUT3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ONECUT3 O60422 ZMYND12 Homo sapiens Q9H0C1
Y2H Prey Pooling
32296183
Intra
ONECUT3 O60422 ZMYND12 Homo sapiens Q9H0C1
Validated Y2H
32296183
Intra
ONECUT3 O60422 ZMYND12 Homo sapiens Q9H0C1
Y2H Array
32296183
Intra
ONECUT3 O60422 CIB1 Homo sapiens Q99828
Validated Y2H
32296183
Intra
ONECUT3 O60422 CIB1 Homo sapiens Q99828
Y2H Prey Pooling
32296183
Intra
ONECUT3 O60422 CIB1 Homo sapiens Q99828
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Osteogenesis Imperfecta, Type Xvi

  • Osteogenesis Imperfecta Type 16

  • OI16

  • Oi, Type Xvi

  • Osteogenesis Imperfecta Type Xvi

  • Chromosome 11p11.2 Deletion Syndrome 91.3-Kb

  • Osteogenesis Imperfecta 16

  • Chromosome 11p11.2 Deletion Syndrome, 91.3-Kb
Dracunculiasis

  • Guinea Worm Disease

  • Dracontiasis

  • Dracunculosis

  • Infection By Dracunculus Medinensis

  • Gwd

  • Guinea Worm Infection

  • Parasitic Infection Caused By Dracunculus Medinensis

  • Medina Worm Disease

  • Medinensis

  • Medina Worm Infestation

  • Dracunculus Medinensis Infestation

  • Guinea Worm Infestation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09787 ONECUT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ONECUT3 RGD RGD:1591005
Felis catus ONECUT3 VGNC VGNC:102652
Mus musculus ONECUT3 MGD MGI:1891409
Canis familiaris ONECUT3 VGNC VGNC:44124
Others ONECUT3 NCBI