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Cat. No.: HY-122216

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LY 88329

LY 88329 is a potent narcotic antagonist.

For research use only. We do not sell to patients.

CAS No.: 78693-86-4
Formula: C₂₅H₂₉NO₆
Molecular Weight:439.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

LY 88329 Chemical Structure

CAS No.: 78693-86-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

LY 88329 is a potent narcotic antagonist^[1].

In Vivo

LY 88329 (0.16, 0.32, 0.64, 1.25, 2.5, 5 mg/kg; intramuscular injection; twice a week) shows narcotic antagonist activity in pigeons^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Male White Carneaux pigeons^[1]
Dosage:

0.16, 0.32, 0.64, 1.25, 2.5, 5 mg/kg (20 mg/kg of morphine)
Administration:

Intramuscular injection; twice a week
Result:

Produced some antagonism of the effects of 20 mg/kg of morphine, bringing suppressed rates of responding back towards the 100% of control level and reversing the morphine-induced decrease in quarter-life value in birds.

Chemical Information

CAS No. 78693-86-4
Molecular Weight 439.50
Formula C₂₅H₂₉NO₆
SMILES

O=C(CCN1C[C@H]([C@H](CC1)C2=CC=CC(O)=C2)C)C3=CC=CC=C3.O=C(/C=C\C(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leander JD. Behavioral effects of phenylpiperidine narcotic antagonists. Pharmacol Biochem Behav. 1981 Jul;15(1):65-70. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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