PreQ1-DBCO
PreQ1-DBCO is a strained cyclooctyne commonly used in click chemistry. PreQ1-DBCO undergoes TGT-catalyzed guanine base exchange in DNA oligonucleotide stem-loops to replace guanine. PreQ1-DBCO functionalizes custom DNA oligonucleotide sequences. DBCO-modified DNA oligonucleotides are conjugated with azide peptides via strain-promoted azide-alkyne click chemistry (SPAAC). PreQ1-DBCO can be used in studies of hemophilia B (Christmas disease).
For research use only. We do not sell to patients.
- Formula: C34H39N7O3
- Molecular Weight:593.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 593.72
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Formula C34H39N7O3
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SMILES
O=C(NCCCCCCNCC1=CNC(N=C(N2)N)=C1C2=O)CCCCC(N3CC4=C(C#CC5=C3C=CC=C5)C=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PreQ1-DBCO Related Classifications
Cat. No.: HY-185423
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- PreQ1-DBCO
- DNA/RNA Synthesis
- Biochemical Assay Reagents
- hemophilia b
- SPAAC
- DNA oligonucleotide-peptide conjugate
- azide-modified peptides
- DNA oligonucleotide stem loops
- TGT
- strain-promoted azide-alkyne cycloaddition
- DBCO-modified DNA
- triazole linkages
- E. coli tRNA guanine transglycosylase
- Inhibitor
- inhibitor
- inhibit