EEF2K
EEF2K stands out in this atypical-kinase collection as the only alpha-kinase dedicated to translational control: it phosphorylates elongation factor eEF2 on Thr56, blocking eEF2 binding to the ribosome and slowing polypeptide chain elongation. The kinase is activated by Ca2+/calmodulin and is restrained by mTORC1- and p70S6K-mediated phosphorylation, allowing nutrient and growth signals to tune elongation rates in real time. Because many tumor cells rely on EEF2K to survive energetic stress and chemotherapy, it is an active target in oncology drug discovery. Recombinant EEF2K supports kinase assays, inhibitor screening and studies linking calcium signaling to protein synthesis.
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EEF2K Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
