Depatuxizumab MMAE
Based on 1 Customer Validation
Depatuxizumab MMAE is an antibody-drug conjugate (ADC) comprising an anti EGFR monoclonal antibody (Depatuxizumab) (HY-P99849) and the cytotoxic agent Monomethyl auristatin E (MMAE) (HY-15162). Depatuxizumab MMAE can be used for the study of EGFR-expressing advanced solid tumors.
For research use only. We do not sell to patients.
- Purity : 99.73%
- Molecular Weight:148000 (average)
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Storage:
-80°C, protect from light
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
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X15695ERα Degarder -
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Trastuzumab emtansineAntibody-drug Conjugate -
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Patritumab deruxtecanHER3-Directed ADC -
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Cetuximab MMAEADC -
![2-Methyl-2-propanyl(1S,8R)-4-nitro-11-azatricyclo[6.2.1.02,7]undeca-2,4,6-triene-11-carboxylate](https://file.medchemexpress.com/product_pic/hy-77304.gif)
HY-77304
2-Methyl-2-propanyl(1S,8R)-4-nitro-11-azatricyclo[6.2.1.02,7]undeca-2,4,6-triene-11-carboxylateDrug Intermediate -
HY-164153
ADC Control Human IgG1-vcMMAE (DAR4, solution)Isotype Control
All EGFR Isoforms
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Biological Activity
Description
Chemical Information
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Appearance Liquid
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Molecular Weight 148000 (average)
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Color Colorless to light yellow
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SMILES
[Depatuxizumab MMAE]
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light
Protocols
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
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Data Sheet (238 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Depatuxizumab MMAE Related Classifications
HY-156712 Related Classifications
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