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Cat. No.: HY-177107

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DGK-IN-10

DGK-IN-10 (example 61) is a DGK inhibitor with IC₅₀ values of ≤ 10 nM for both DGKα and DGKζ. DGK-IN-10 can be used for the research of diseases including cancer.

For research use only. We do not sell to patients.

CAS No.: 3075645-89-2
Formula: C₂₈H₃₇F₃N₆O₂
Molecular Weight:546.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DGK-IN-10 Chemical Structure

CAS No.: 3075645-89-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DGK-IN-10 (example 61) is a DGK inhibitor with IC₅₀ values of ≤ 10 nM for both DGKα and DGKζ. DGK-IN-10 can be used for the research of diseases including cancer^[1].

Chemical Information

CAS No. 3075645-89-2
Molecular Weight 546.63
Formula C₂₈H₃₇F₃N₆O₂
SMILES

O=C(N1C)N=C(N2C[C@H](N(C[C@@H]2C)[C@H](C3=CC=C(C=C3)C(F)(F)F)C)CC)C(N=C4C)=C1N4C[C@@H]5CCCO5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Joshua HUMMEL, et al. Bicyclic dgk inhibitors. WO2025043151A2. 2025-02-27.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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