DiPODS
DiPODS is a thiolate-targeted bioconjugation reagent with irreversible covalent binding activity. DiPODS can rebridge the broken disulfide bonds in antibodies/Fab fragments. DiPODS enables site-specific bioconjugation to generate homogeneous immunoconjugates. DiPODS can conjugate with various payloads via the primary amine at the end of its side chain. DiPODS is applicable to breast cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 2756320-37-1
- Formula: C23H32N6O11S2
- Molecular Weight:632.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
FabHER2-DiPODS-FITC (0.8 mg/mL; 30 min) retains specific binding to HER2-positive BT474 human breast cancer cells and exhibits higher immunoreactivity than a non-site-specific lysine-conjugated analogue[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2756320-37-1
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Molecular Weight 632.66
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Formula C23H32N6O11S2
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SMILES
O=C(CCOCCOCCOCCOCCN)NC1=CC(C2=NN=C(S(=O)(C)=O)O2)=CC(C3=NN=C(S(=O)(C)=O)O3)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DiPODS Related Classifications
HY-186282 Related Classifications
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