Diproteverine
Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties.
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- CAS No.: 69373-95-1
- 화학식: C26H35NO4
- 분자량:425.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley virgin female rats[1]
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Dosage:40, 80, 160, 320 mg/kg
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Administration:P.o.; daily for 10 days
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Result:Induced embryonic deaths, significantly increased incidence of fetuses showing an unusual pattern of digital, tail, heart, and vertebral abnormalities.
Chemical Information
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CAS No. 69373-95-1
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분자량 425.56
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화학식 C26H35NO4
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SMILES
CC(C)OC1=CC2=C(CCN=C2CC3=CC=C(C(OCC)=C3)OCC)C=C1OC(C)C
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Synonyms
BRL 40015
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Ridings JE, et al. Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. [Content Brief]
[2]. Lacroix P, et al. Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)