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Cat. No.: HY-P3811

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Autocamtide-3

Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca²⁺/calmodulin-dependent kinase II) (CaMK) substrate.

For research use only. We do not sell to patients.

CAS No.: 142828-10-2
Formula: C₆₅H₁₁₃N₂₁O₂₀
Molecular Weight:1508.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Autocamtide-3 Chemical Structure

CAS No.: 142828-10-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca²⁺/calmodulin-dependent kinase II) (CaMK) substrate^[1].

IC₅₀ & Target^[1]

CaMK II

All CaMK Isoforms :

In Vitro

20 μM Autocamtide-3 (H2N-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-COOH), and 5 μL of CaMKII is used in a 50 μL kinase-assay reaction. Autocamtide-3 shows catalytic activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 142828-10-2
Molecular Weight 1508.72
Formula C₆₅H₁₁₃N₂₁O₂₀
Sequence Shortening

KKALHRQETVDAL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mehtap Yilmaz, et al. Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity. Biosci Rep. 2013 Feb 7;33(2):e00024. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Autocamtide-3

All CaMK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Autocamtide-3 Related Classifications

HY-P3811 Related Classifications