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Cat. No.: HY-N3003

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Darutigenol

Darutigenol is an ent-pimarane-type diterpenoid isolated from Siegesbecikia orientalis L..

For research use only. We do not sell to patients.

CAS No.: 5940-00-1
Formula: C₂₀H₃₄O₃
Molecular Weight:322.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Darutigenol Chemical Structure

CAS No.: 5940-00-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Darutigenol is an ent-pimarane-type diterpenoid isolated from Siegesbecikia orientalis L.^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	>100 μg/mL Compound: 6	Cytotoxicity against human HeLa cells after 44 hrs by MTT assay Cytotoxicity against human HeLa cells after 44 hrs by MTT assay	[PMID: 19928884]
MDA-MB-231	IC₅₀	>10 μM Compound: 20	Antiinvasive activity in human MDA-MB-231 cells assessed as inhibition of EGF-induced cell invasion after 3.5 hrs Antiinvasive activity in human MDA-MB-231 cells assessed as inhibition of EGF-induced cell invasion after 3.5 hrs	[PMID: 28009521]
MDA-MB-231	IC₅₀	>25 μM Compound: 6a	Inhibition of EGF-induced invasion of human MDA-MB-231 cells by MTT assay Inhibition of EGF-induced invasion of human MDA-MB-231 cells by MTT assay	[PMID: 28302401]
RAW264.7	IC₅₀	>100 μM Compound: 20	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 28009521]

Chemical Information

CAS No. 5940-00-1
Molecular Weight 322.48
Formula C₂₀H₃₄O₃
SMILES

C[C@]12[C@@]3([H])C(CC[C@]1([H])C(C)([C@H](O)CC2)C)=C[C@]([C@@H](O)CO)(C)CC3
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Giang PM, et al. ent-pimarane-type diterpenoids from Siegesbeckia orientalis L. Chem Pharm Bull (Tokyo). 2005 Feb;53(2):232-4. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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Darutigenol

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

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References

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Darutigenol Related Classifications

HY-N3003 Related Classifications