Diproteverine
Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties.
For research use only. We do not sell to patients.
- CAS No.: 69373-95-1
- Formula: C26H35NO4
- Molecular Weight:425.56
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
More
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Sprague-Dawley virgin female rats[1]
-
Dosage:40, 80, 160, 320 mg/kg
-
Administration:P.o.; daily for 10 days
-
Result:Induced embryonic deaths, significantly increased incidence of fetuses showing an unusual pattern of digital, tail, heart, and vertebral abnormalities.
Chemical Information
-
CAS No. 69373-95-1
-
Molecular Weight 425.56
-
Formula C26H35NO4
-
SMILES
CC(C)OC1=CC2=C(CCN=C2CC3=CC=C(C(OCC)=C3)OCC)C=C1OC(C)C
-
Synonyms
BRL 40015
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ridings JE, et al. Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. [Content Brief]
[2]. Lacroix P, et al. Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)