Erlosiban
Erlosiban (OBE001) is an orally active non-peptide type oxytocin receptor antagonist. Erlosiban inhibits the increase of intracellular calcium concentration, thereby reducing uterine smooth muscle contraction. Erlosiban can be used for research on premature birth and to improve embryo implantation and pregnancy rate in assisted reproductive technology (AR).
For research use only. We do not sell to patients.
- CAS No.: 1477482-19-1
- Formula: C20H22N2O3
- Molecular Weight:338.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1477482-19-1
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Molecular Weight 338.40
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Formula C20H22N2O3
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SMILES
O=C(N1C/C(C[C@H]1CO)=N\OC)C2=CC=C(C3=CC=CC=C3C)C=C2
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Synonyms
OBE001
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Pohl O, et al. Effects of the Oral Oxytocin Receptor Antagonist Tocolytic OBE001 on Reproduction in Rats. Reprod Sci. 2016 Apr;23(4):439-47. [Content Brief]
[2]. Pohl O, et al. Pharmacokinetic interactions of OBE001 and betamethasone in healthy female volunteers. J Clin Pharm Ther. 2015 Jun;40(3):328-32. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Erlosiban Related Classifications
HY-16741 Related Classifications
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