EZH2-IN-13
Based on 1 Customer Validation
EZH2-IN-13 is a potent EZH2 inhibitor, for details please refer to compound 73 in patent WO2017139404. EZH2-IN-13 can be used to study cancers or precancerous lesions associated with EZH2 activity.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 1403255-41-3
- Formula: C34H45N5O3
- Molecular Weight:571.75
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Histone Methyltransferase Isoforms
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Biological Activity
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EZH2 |
Chemical Information
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CAS No. 1403255-41-3
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Appearance Solid
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Molecular Weight 571.75
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Formula C34H45N5O3
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Color Off-white to light yellow
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SMILES
O=C(C1=CC(C2=CC=C(CN3CCNCC3)C=C2)=CC(N(C4CCOCC4)CC)=C1C)NCC5=C(C)C=C(C)NC5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (218.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7490 mL | 8.7451 mL | 17.4902 mL | 43.7254 mL |
| 5 mM | 0.3498 mL | 1.7490 mL | 3.4980 mL | 8.7451 mL | |
| 10 mM | 0.1749 mL | 0.8745 mL | 1.7490 mL | 4.3725 mL | |
| 15 mM | 0.1166 mL | 0.5830 mL | 1.1660 mL | 2.9150 mL | |
| 20 mM | 0.0875 mL | 0.4373 mL | 0.8745 mL | 2.1863 mL | |
| 25 mM | 0.0700 mL | 0.3498 mL | 0.6996 mL | 1.7490 mL | |
| 30 mM | 0.0583 mL | 0.2915 mL | 0.5830 mL | 1.4575 mL | |
| 40 mM | 0.0437 mL | 0.2186 mL | 0.4373 mL | 1.0931 mL | |
| 50 mM | 0.0350 mL | 0.1749 mL | 0.3498 mL | 0.8745 mL | |
| 60 mM | 0.0292 mL | 0.1458 mL | 0.2915 mL | 0.7288 mL | |
| 80 mM | 0.0219 mL | 0.1093 mL | 0.2186 mL | 0.5466 mL | |
| 100 mM | 0.0175 mL | 0.0875 mL | 0.1749 mL | 0.4373 mL |