Metixene
Based on 2 publication(s) in Google Scholar
Metixene (Piperidine) is an anticholinergic and antiparkinsonian agent. Metixene potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC50 and Ki values of 55 nM and 15 nM, respectively. Metixene can be used for the research of parkinsonian.
For research use only. We do not sell to patients.
- CAS No.: 4969-02-2
- Formula: C20H23NS
- Molecular Weight:309.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Metixene
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Biological Activity
Metixene can potentially inhibit the binding of QNB with the muscarinic receptor, IC50 and Ki values of 55 nM and 15 nM, respectively[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4969-02-2
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Molecular Weight 309.47
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Formula C20H23NS
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SMILES
CN1CC(CC2C3=C(SC4=C2C=CC=C4)C=CC=C3)CCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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bioRxiv
2020 Jul 27:2020.05.23.112235. PMID: 32511370
Purity & Documentation
References
[1]. Syvälahti EK, et al. Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung. Pharmacol Toxicol. 1988 Feb;62(2):90-4. [Content Brief]
[3]. S L Levin, et al. Dualism in the effect of cholinolytics upon the human parotid gland deprived of parasympathetic control. Int J Clin Pharmacol Res. 1986;6(5):429-39. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Metixene Related Classifications
HY-120081 Related Classifications
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