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United States

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Cat. No.: HY-169012

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PSB-21110

PSB-21110 is an irreversible SARS-CoV-2 Mpro inhibitor with EC₅₀ value of 2.68 nM. PSB-21110 has antiviral activity.

For research use only. We do not sell to patients.

Formula: C₁₄H₁₁ClFNO₃
Molecular Weight:295.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PSB-21110 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PSB-21110 is an irreversible SARS-CoV-2 Mpro inhibitor with EC₅₀ value of 2.68 nM. PSB-21110 has antiviral activity^[1].

Chemical Information

Molecular Weight 295.69
Formula C₁₄H₁₁ClFNO₃
SMILES

ClC1=CN=CC(OC(C2=CC=C(OCC)C=C2F)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Oneto A, et al. Nonpeptidic Irreversible Inhibitors of SARS-CoV-2 Main Protease with Potent Antiviral Activity. J Med Chem. 2024 Sep 12;67(17):14986-15011. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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