TABS
TABS (N-Tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid) is a zwitterionic chemical buffering agent, is broadly applied in cell culture.
For research use only. We do not sell to patients.
- CAS No.: 54960-65-5
- Formula: C8H19NO6S
- Molecular Weight:257.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 54960-65-5
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Molecular Weight 257.30
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Formula C8H19NO6S
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SMILES
O=S(O)(CCCCNC(CO)(CO)CO)=O
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Synonyms
N-Tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Directly Induced Neuron Culture
Directly induced neuron culture converts somatic cells, most commonly fibroblasts, into induced neurons without passing through a pluripotent or neural progenitor stage; classic evidence shows that mouse fibroblasts can be converted by Ascl1, Brn2/Pou3f2, and Myt1l, human fibroblasts can be converted by defined neuronal transcription factors, and human fibroblasts can also be converted by miR-9/9-124 with neurogenic or subtype-specifying transcription factors. The readout is acquisition of neuronal identity and function, assessed by neuronal morphology, neuronal markers such as Tuj1/βIII-tubulin, MAP2, synapsin, and subtype markers when relevant, together with functional assays such as action-potential firing, synaptic activity, and electrophysiology.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TABS Related Classifications
HY-W643127 Related Classifications
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