Docetaxel Trihydrate (Standard)
Docetaxel Trihydrate (Standard) (RP-56976 Trihydrate (Standard)) is the analytical standard of Docetaxel Trihydrate (HY-B0011A). This product is intended for research and analytical applications. Docetaxel Trihydrate (RP-56976 Trihydrate) is an orally active tubulin stabilizer with antitumor activity. Docetaxel Trihydrate is a P-glycoprotein substrate and is metabolized by CYP3A to inactive products. Docetaxel Trihydrate binds tubulin, promotes tubulin polymerization, and inhibits microtubule depolymerization. Docetaxel Trihydrate induces aberrant mitosis followed by necrotic-like cell death at low concentrations, and induces G2/M mitotic arrest and drives apoptosis at high concentrations. Docetaxel Trihydrate induces renal injury/renal alterations, sex-dependent granule toxicity/uptake, low cardiac delivery, and decreased hepatic SOD/increased catalase/hepatotoxicity. Docetaxel Trihydrate can be used in cancer-related research.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 148408-66-6
- Formula: C43H59NO17
- Molecular Weight:861.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-B0011A
Docetaxel TrihydrateTubulin Stabilizer -
HY-B0011
DocetaxelTubulin Stabilizer -
HY-17029
Epothilone BMicrotubule Stabilizer -
HY-13442A
Eribulin mesylateMicrotubule Inhibitor -
HY-B0015
PaclitaxelAntitumor Agent -
HY-13503
Epothilone ATubulin Competitive Inhibitor -
HY-13442
EribulinMicrotubule Inhibitor -
HY-15459
Cabazitaxel -
HY-16569
ColchicineTubulin Inhibitor -
HY-B0011R
Docetaxel (Standard)Reference Standard -
HY-17583
GriseofulvinAntifungal Antibiotic -
HY-17449
Fosbretabulin disodiumTubulin Destabilizing Agent
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 148408-66-6
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Molecular Weight 861.93
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Formula C43H59NO17
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SMILES
O=C(OC(C)(C)C)N[C@H]([C@H](C(O[C@@H]1C(C)=C([C@@H](O)C([C@@]2(C)[C@]([C@@](CO3)(OC(C)=O)[C@@]3([H])C[C@@H]2O)([H])[C@@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[C@@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O
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Synonyms
RP-56976 Trihydrate (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Docetaxel Trihydrate (Standard) Related Classifications
HY-B0011AR Related Classifications
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