DPPE-PEG2000-MTP
DPPE-PEG2000-MTP (DPPE-PEG2000-Mal-Cys-ASSLNIA) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an MTP (HY-P10643) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-MTP can be used in research on muscle-targeted drug delivery and muscle tissue gene delivery.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
DPPE-PEG2000-MTP is composed of three covalently linked components: 1. DPPE (1,2-dipalmitoyl-sn-glycerol-3-phosphoethanolamine): Lipid anchoring group-inserts into the lipid bilayer of liposomes/LNPs, providing stable membrane anchoring; its saturated C16 chain imparts bilayer rigidity. 2. PEG 2000 (polyethylene glycol, molecular weight 2000): Hydrophilic polymer spacer arm-forms a steric hindrance crown around nanoparticles, reducing opsonin activity and reticuloendothelial system (RES) clearance, prolonging circulating half-life, and providing steric separation between the lipid surface and the targeting ligand. 3. MTP peptide: Targeting/functional ligand-MTP peptide is a muscle-targeting peptide that mediates the targeted delivery of the carrier to muscle tissue, increasing drug accumulation in muscle tissue.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
[DPPE-PEG2000-MTP]
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別名
DPPE-PEG2000-Mal-Cys-ASSLNIA
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DPPE-PEG2000-MTP 関連分類
HY-187745A 関連分類
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