Duocarmycin analog-2
Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 1164275-01-7
- Formula: C29H23ClN4O3
- Molecular Weight:510.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Duocarmycin analog-2 (72 h) has anti-proliferative activity with IC50 values of 0.001, 0.002, 0.002, 0.004, 0.009, 0.01, 0.015, 0.019, 0.019, 0.019, 0.02, 0.04, and 0.068 nM for DU4475, SET2, HCT 16, A2780, MDA MB468, LNCaP, LS174T, CCRF-CEM, COLO205, H2087, H661, A549, and MCD MB231 cells, respectively.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1164275-01-7
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Molecular Weight 510.97
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Formula C29H23ClN4O3
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SMILES
ClC[C@H]1C2=C(C=C(C3=CC=CC=C32)O)N(C1)C(C4=CC5=CC(NC(C6=CC=C(C=C6)N)=O)=CC=C5N4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Duocarmycin analog-2 Related Classifications
HY-148091 Related Classifications
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