BODIPY Dyes

BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins.

BODIPY FL hydrazide hydrochloride is a BODIPY-containing hydrazide fluorescent dye. BODIPY FL hydrazide hydrochloride is used to label carbonyl groups on oxidatively damaged proteins, 3-ketosteroids, and heparin/heparan sulfate carbohydrates. BODIPY FL hydrazide hydrochloride specifically binds to protein carbonyls, steroid keto groups, or reducing-end carbonyls of carbohydrates through derivatization or reductive amination via its hydrazide group to form stable conjugates; after the reaction is complete, the labeled molecules emit strong fluorescence (Ex/Em = 488-495/516-520 nm).

BODIPY TMR amide NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

BODIPY 650/665 NHS ester is a bright far-red fluorescent dye. Its excitation/emission wavelengths are Ex/Em = 646/660 nm.

Tracer AL244 is a BODIPY-based fluorescent tracer and also a TRIM21 binder. Tracer AL244 enables evaluation of TRIM21 target binding in both intact and permeabilized cells.

BODIPY 480/508-cholesteryl oleate is a fluorescently tagged derivative of Cholesteryl oleate (HY-113217). BODIPY 480/508-cholesteryl oleate can be used to monitor lipid transport mechanisms in mammalian cells (Ex/Em = 480/508 nm).

CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC₅₀ of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models.

BODIPY TMR acid is a fluorescent dye. BODIPY TMR acid is a high quantum yield fluorophore which can be coupled with Rebastinib.

QPy-TPA is a lipopjilc probes, which induces non-ferroptotic cell death and lipid dynamic regularion in B16 and HepG2 cells upon light irradiation. QPy-TPA reveals a maximum absorption wavelength of 400 nm and a maximum emission wavelength of 590 nm.

BODIQPy-TPA is a lipophilic probes, which induces ferroptosis in B16 and HepG2 cells upon light irradiation through lipid peroxidation. BODIQPy-TPA reveals a maximum absorption wavelength of 488 nm and a maximum emission wavelength above 640 nm.

BODIPY-phenyl-amide-alkyne (compound 6) is an alkyne-containing OFF-to-ON fluorophore. BODIPY-phenyl-amide-alkyne is a BODIPY derivative that can be conjugated to protein IL-33 Y143azidoPhe via CuAAC reaction.

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases.

Bodipy TMR-X muscimol is a Bodipy labeled Muscimol (HY-N2313) (Ex=543 nm, Em=572 nm). Muscimol is a GABAA agonist. Bodipy TMR-X muscimol can be used for imaging the spread of reversible brain inactivations.

BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1.

8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λ_abs=502 nm, λ_em=516 nm) (*abs: main absorption maxima).

BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λ_ex=504 nm, λ_em=510 nm).

BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers.

BODIPY FL SSE is a potent fluorescent dye. BODIPY FL SSE is used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY FL SSE can reactive with primary amines on biomolecules to emit green fluorescence. (λ_ex=502 nm, λ_em=511 nm).

BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image.

BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions.