E7766 disodium
Based on 5 publication(s) in Google Scholar
E7766 disodium is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 disodium shows potent pan-genotypic and antitumor activities.
For research use only. We do not sell to patients.
- CAS No.: 2242636-28-6
- Formula: C24H26F2N10Na2O8P2S2
- Molecular Weight:792.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) E7766 disodium
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2242636-28-6
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Molecular Weight 792.58
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Formula C24H26F2N10Na2O8P2S2
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SMILES
F[C@@H]1[C@H](O[P@]2(S)=O)[C@@H](CO[P@]3(S)=O)O[C@H]1[N@]4C5=NC=NC(NC/C=C/CNC6=C(N=C[N@]7[C@@H]8O[C@H](CO2)[C@@H](O3)[C@H]8F)C7=NC=N6)=C5N=C4.[Na].[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Science
2026 May 7;392(6798):eadx1893. PMID: 42096576 -
Science
2025 Oct 9;390(6769):eadl4089. PMID: 41066563 -
J Exp Med
2026 May 4;223(5):e20251796. PMID: 41874365 -
Cancer Biol Med
Antitumor effects of STING agonists on nervous system tumors via tumor-intrinsic STING-STAT1-mediated HMGN2 expression. [Abstract]2026 Feb 16;23(1):133-153. PMID: 41700809 -
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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