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Cat. No.: HY-161602

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EGFR/HER2-IN-13

EGFR/HER2-IN-13 (Compd 38) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-13 can be used for cancer research.

For research use only. We do not sell to patients.

CAS No.: 3034701-46-4
Formula: C₂₇H₃₆N₈O₃
Molecular Weight:520.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

EGFR/HER2-IN-13 Chemical Structure

CAS No.: 3034701-46-4

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Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

EGFR/HER2-IN-13 (Compd 38) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-13 can be used for cancer research^[1].

All EGFR Isoforms :

In Vitro

EGFR/HER2-IN-13 shows IC₅₀s bellow 100 nM against insASV, insSVD, insGSP mutants EGFRs transformed Ba/F3 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3034701-46-4
Molecular Weight 520.63
Formula C₂₇H₃₆N₈O₃
SMILES

CN1C2=NC(NC3=C(OC)C=C(N(C)CCN(C)C)C(NC(C=C)=O)=C3)=NC=C2CN(C45CC(C5)C4)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. John H, et al. Inhibitors of egfr or her2 and methods of use. WO2024073745A1. 2024-04-04

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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EGFR/HER2-IN-13

All EGFR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

EGFR/HER2-IN-13 Related Classifications

HY-161602 Related Classifications