Eniporide mesylate
Based on 1 publication(s) in Google Scholar
Eniporide mesylate (EMD 96785 mesylate) is a Na(+)/H(+) exchange (NHE) inhibitor. Eniporide mesylate specifically inhibits the NHE-1 isoform. Eniporide mesylate improves cardiac performance inhibition associated with myocardial ischemia/reperfusion in animals, and limits infarct size in experimental models. Eniporide mesylate regulates cardiac performance and high-energy phosphate content.
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- CAS No.: 190368-98-0
- Formula: C15H20N4O6S2
- Molecular Weight:416.47
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Storage:
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Eniporide mesylate
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Biological Activity
Chemical Information
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CAS No. 190368-98-0
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Molecular Weight 416.47
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Formula C15H20N4O6S2
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SMILES
O=C(C1=C(C)C=C(N2C=CC=C2)C(S(=O)(C)=O)=C1)NC(N)=N.O=S(O)(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Sci Rep
Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1. [Abstract]2020 Apr 2;10(1):5800. PMID: 32242030
Purity & Documentation
References
[1]. Zeymer U, et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50. [Content Brief]
[2]. Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb;77(2):658-63. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Eniporide mesylate Related Classifications
HY-106150A Related Classifications
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