ent-Yahazunol
ent-Yahazunol is a sesquiterpene hybrid growth inhibitor present in sponges of the genus Dysidea. ent-Yahazunol selectively inhibits the growth of human mammary adenocarcinoma cells and human lung cancer cells. ent-Yahazunol can be used in studies related to mammary adenocarcinoma and lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 852945-54-1
- Formula: C21H32O3
- Molecular Weight:332.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
17.4 μM
Compound: 4
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Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
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[PMID: 15921404] |
| HepG2 | EC50 |
50 μM
Compound: 4
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Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
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[PMID: 34653771] |
| MCF7 | EC50 |
50 μM
Compound: 4
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Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
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[PMID: 34653771] |
| MDA-MB-231 | GI50 |
27.7 μM
Compound: 4
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Cytotoxicity against human MDA-MB-231 cells by SRB assay
Cytotoxicity against human MDA-MB-231 cells by SRB assay
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[PMID: 15921404] |
In Vitro
ent-Yahazunol (compound 4) inhibits the growth of MDA-MB-231 mammary gland adenocarcinoma cells with a GI50 of 27.7 μM and A-549 lung carcinoma cells with a GI50 of 17.4 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 852945-54-1
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Molecular Weight 332.48
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Formula C21H32O3
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SMILES
C[C@@]12[C@H]([C@](O)(CC[C@@]1([H])C(C)(CCC2)C)C)CC3=C(C=CC(O)=C3)O
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Structure Classification
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Initial Source
sponge
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ent-Yahazunol Related Classifications
HY-N20658 Related Classifications
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