Eperisone-d10 hydrochloride
Based on 1 Customer Validation
Eperisone-d10 (hydrochloride) is the deuterium labeled Eperisone hydrochloride. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[2 .
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 1246819-46-4
- Formula: C17H16D10ClNO
- Molecular Weight:305.91
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 1246819-46-4
-
Unlabeled Cas 56839-43-1
-
Appearance Solid
-
Molecular Weight 305.91
-
Formula C17H16D10ClNO
-
SMILES
C(C(CN1C(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C)(=O)C2=CC=C(CC)C=C2.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 54 mg/mL (176.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Cabitza P, et al. Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev Med Pharmacol Sci. 2008 Jul-Aug;12(4):229-35. [Content Brief]
[4]. Bavage S, et al. Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. Pharmacol Rep. 2016 Oct;68(5):903-12. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2689 mL | 16.3447 mL | 32.6894 mL | 81.7234 mL |
| 5 mM | 0.6538 mL | 3.2689 mL | 6.5379 mL | 16.3447 mL | |
| 10 mM | 0.3269 mL | 1.6345 mL | 3.2689 mL | 8.1723 mL | |
| 15 mM | 0.2179 mL | 1.0896 mL | 2.1793 mL | 5.4482 mL | |
| 20 mM | 0.1634 mL | 0.8172 mL | 1.6345 mL | 4.0862 mL | |
| 25 mM | 0.1308 mL | 0.6538 mL | 1.3076 mL | 3.2689 mL | |
| 30 mM | 0.1090 mL | 0.5448 mL | 1.0896 mL | 2.7241 mL | |
| 40 mM | 0.0817 mL | 0.4086 mL | 0.8172 mL | 2.0431 mL | |
| 50 mM | 0.0654 mL | 0.3269 mL | 0.6538 mL | 1.6345 mL | |
| 60 mM | 0.0545 mL | 0.2724 mL | 0.5448 mL | 1.3621 mL | |
| 80 mM | 0.0409 mL | 0.2043 mL | 0.4086 mL | 1.0215 mL | |
| 100 mM | 0.0327 mL | 0.1634 mL | 0.3269 mL | 0.8172 mL |
Eperisone-d10 hydrochloride Related Classifications
HY-B1901S Related Classifications
Powered by Bioz