ES-8891
ES-8891 is a renin inhibitor. Oral administration of ES-8891 to normotensive sodium-depleted macaques for one week significantly reduced plasma renin activity, immunoreactive renin concentrations, and plasma angiotensin I concentrations, while mean blood pressure decreased significantly, without significant changes in heart rate. ES-8891 regulates blood pressure by inhibiting plasma renin levels and renal renin synthesis.
For research use only. We do not sell to patients.
- CAS No.: 129445-88-1
- Formula: C42H60N6O6S
- Molecular Weight:777.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 129445-88-1
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Molecular Weight 777.03
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Formula C42H60N6O6S
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SMILES
O=C(NCCCCCC)C[C@H](O)[C@@H](NC([C@@H](NC([C@@H](NC(CN1CCOCC1)=O)CC2=C3C=CC=CC3=CC=C2)=O)CC4=CSC=N4)=O)CC5CCCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ES-8891 Related Classifications
HY-117913 Related Classifications
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