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Cat. No.: HY-N8415

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Hispanone

Hispanone, a diterpenoidcan, has anti-inflammatory activity. Hispanone can be isolated from Leonurus heterophyllus.

For research use only. We do not sell to patients.

CAS No.: 82462-67-7
Formula: C₂₀H₂₈O₂
Molecular Weight:300.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Hispanone Chemical Structure

CAS No.: 82462-67-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Hispanone, a diterpenoidcan, has anti-inflammatory activity. Hispanone can be isolated from Leonurus heterophyllus^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
Neutrophil	IC₅₀	5.42 μM Compound: 5	Antiinflammatory activity in human neutrophils assessed as inhibition of elastase release Antiinflammatory activity in human neutrophils assessed as inhibition of elastase release	[PMID: 32818604]
Neutrophil	IC₅₀	8.48 μM Compound: 5	Antiinflammatory activity in human neutrophils assessed as inhibition of fMLF/cytochalasin B-induced superoxide anion generation Antiinflammatory activity in human neutrophils assessed as inhibition of fMLF/cytochalasin B-induced superoxide anion generation	[PMID: 32818604]

Chemical Information

CAS No. 82462-67-7
Molecular Weight 300.44
Formula C₂₀H₂₈O₂
SMILES

O=C1C[C@@]2([H])C(C)(C)CCC[C@]2(C)C(CCC3=COC=C3)=C1C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Giang PM, et al. New labdane-type diterpenoids from Leonurus heterophyllus SW. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):938-41. [Content Brief]

[2]. Jing Qin, et al. New labdane diterpenoids from Leonurus japonicus and their anti-inflammatory activity. Phytochemistry Letters. 2014, 10, 313-317.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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