MC1
MC1 is a potent NLRP3 inhibitor with a KD value of 19.3 nM. MC1 shows no cytotoxicity. MC1 ameliorates cognitive deficits without eliciting adverse effects and shows an absence of hepatotoxicity. MC1 has the potential for the research of Alzheimer's disease (AD).
For research use only. We do not sell to patients.
- Formula: C23H23N3O6S2
- Molecular Weight:501.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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NLRP3 19.3 nM (Kd) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 501.58
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Formula C23H23N3O6S2
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SMILES
O=C(NS(C1=CC(C(C)(O)C)=CS1)(=O)=O)NC2=C(C3=CC=C([N+]([O-])=O)C=C3)C=CC4=C2CCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)