Antitumor agent-41
Antitumor agent-41 (compound N-12), a potent antitumor agent, enhibits excellent antimigration and anti-invasion activity. Antitumor agent-41 (compound N-12) induces tumor inhibition via tumor necrosis and inflammatory response.
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- No. CAS: 3035564-55-4
- Fòrmula: C64H109IN2O21
- Peso molecular:1369.46
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
>200 μM
Compound: N-12
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Cytotoxicity against human A-431 cells measured after 24 hrs by MTT assay
Cytotoxicity against human A-431 cells measured after 24 hrs by MTT assay
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[PMID: 35073068] |
| CHO | IC50 |
>200 μM
Compound: N-12
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Cytotoxicity against CHO cells measured after 24 hrs by MTT assay
Cytotoxicity against CHO cells measured after 24 hrs by MTT assay
|
[PMID: 35073068] |
| HeLa | IC50 |
>200 μM
Compound: N-12
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Cytotoxicity against human HeLa cells measured after 24 hrs by MTT assay
Cytotoxicity against human HeLa cells measured after 24 hrs by MTT assay
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[PMID: 35073068] |
| N2a | IC50 |
>200 μM
Compound: N-12
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Cytotoxicity against mouse Neuro2a cells measured after 24 hrs by MTT assay
Cytotoxicity against mouse Neuro2a cells measured after 24 hrs by MTT assay
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[PMID: 35073068] |
| PC-12 | IC50 |
>200 μM
Compound: N-12
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Cytotoxicity against rat PC-12 cells measured after 24 hrs by MTT assay
Cytotoxicity against rat PC-12 cells measured after 24 hrs by MTT assay
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[PMID: 35073068] |
Antitumor agent-41 (compound N-12) has obvious inhibitory activity on invasion at a concentration of 50 μM on A431 cell, and the inhibition rate was 36.6 ± 13.9% [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3035564-55-4
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Peso molecular 1369.46
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Fòrmula C64H109IN2O21
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SMILES
O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2CO)OC[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)NC(CCCCCCCCCCCCCCCCC)=O)O)O)O)O[C@@]3(C[C@@H]([C@H]([C@@H](O3)[C@@H]([C@@H](CO)O)O)NC(C4=CC(I)=CC=C4)=O)O)C(O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-41 Related Classifications
HY-144125 Related Classifications
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