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Referencia número: HY-P99854A

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Disitamab (powder)

Name: Disitamab (powder)
Brand: MedChemExpress
SKU: HY-P99854A
Price: 910.00 USD
Availability: PreOrder

(Synonyms: RC48-0 (powder))

1 Cited Publications

Revisión del cliente

Based on 1 publication(s) in Google Scholar

Disitamab (RC48-0) (powder) is a humanized monoclonal antibody targeting HER2. Disitamab (powder) can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985).

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2185868-98-6
Peso molecular:144.16 kDa

Almacenamiento:

Shipping with dry ice

Please store the product under the recommended conditions in the Certificate of Analysis.

Disitamab (powder) Chemical Structure

No. CAS: 2185868-98-6

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Other In-stock Forms of Disitamab (powder)

Disitamab

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Actividad biológica
- Descripciòn
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vivo
- Ensayo clínico
- Gene ID
- Accession
- Conjugated
- Reconstitution
- Format
- Aplicación
Chemical Information
Publications (1)
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Disitamab (RC48-0) (powder) is a humanized monoclonal antibody targeting HER2. Disitamab (powder) can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985)^[1].

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target

HER2

Ver todos los productos específicos de isoformas EGFR :

In Vivo

Disitamab (27 mg/kg; i.v.; once; 5 mL/kg) shows no significant toxicity in monkeys^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ensayo clínico

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Gene ID

2064 [NCBI]

Accession

P04626

Conjugated

Unconjugated

Reconstitution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG1-kappa

Aplicación

ELISA, FACS, Functional assay

Chemical Information

No. CAS 2185868-98-6
Appearance Solid
Peso molecular 144.16 kDa
Color White to off-white
SMILES

[Disitamab (powder)]
Synonyms

RC48-0 (powder)
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Nat Commun

Supramolecular coiled-coil peptide platform for site-specific antibody drug conjugate engineering. [Abstract]

2026 Mar 2. PMID: 41771920

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (257 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Referencias

[1]. Jiang J, et al. Preclinical safety profile of disitamab vedotin：a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Disitamab (powder)

1 Cited Publications

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100 mg

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Actividad biológica
- Descripciòn
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vivo
- Ensayo clínico
- Gene ID
- Accession
- Conjugated
- Reconstitution
- Format
- Aplicación
Chemical Information
Publications (1)
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
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Pureza:
Cantidad:

Disitamab (powder)

Other In-stock Forms of Disitamab (powder)

Publications Citing Use of MedChemExpress (MCE) Disitamab (powder)

Ver todos los productos específicos de isoformas EGFR