Iocarmic acid
Iocarmic acid is a myelographic contrast agent. Iocarmic acid is used for lumbar nerve root angiography and ventriculography. Iocarmic acid induces arachnoiditis via lumbar subarachnoid injection. Iocarmic acid can be used for the research of arachnoiditis.
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- No. CAS: 10397-75-8
- Fòrmula: C24H20I6N4O8
- Peso molecular:1253.86
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Actividad biológica
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Macaque monkeys (5-7 kg)[1]
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Dosage:1.2 mL of 282 mg I/mL
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Administration:intrathecal; single injection
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Result:Induced a consistent myelographic arachnoiditis score of 36 (maximum possible score) across all 4 animals tested.
Produced an average histologic arachnoiditis score of 18, with individual scores ranging from 12 to 20.
Resulted in scores significantly higher than scores for iopamidol, metrizamide, and CSF controls (P < 0.05, Wilcoxon test).
Chemical Information
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No. CAS 10397-75-8
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Peso molecular 1253.86
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Fòrmula C24H20I6N4O8
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SMILES
O=C(C1=C(C(NC(CCCCC(NC2=C(I)C(C(NC)=O)=C(I)C(C(O)=O)=C2I)=O)=O)=C(C(C(NC)=O)=C1I)I)I)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Iocarmic acid Related Classifications
HY-182568 Related Classifications
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