UNC7437
Based on 1 Customer Validation
UNC7437 is a inositol phosphate multikinase (IPMK) inhibitor, with an IC50 value of 26.2 nM. UNC7437 exhibits anti-proliferative activity against glioblastoma cells. UNC7437 decreases the accumulation of InsP4, InsP5, and InsP6 in cells. UNC7437 can be used for the study of TEN-negative glioblastoma models.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.58%
- No. CAS: 2967647-41-0
- Fòrmula: C18H15NO3
- Peso molecular:293.32
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
UNC7437 (400 nM, 48 h) shows significant anti-proliferative activity against human U251-MG glioblastoma cells[1].
UNC7437 (400 nM, 48 h) effectively inhibits inositol phosphate synthesis in human U251-MG glioblastoma cells, significantly decreasing the accumulation of InsP4, InsP5, and InsP6[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2967647-41-0
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Appearance Solid
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Peso molecular 293.32
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Fòrmula C18H15NO3
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Color Light yellow to yellow
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SMILES
O=C(O)/C=C/C1=CC2=C(C3=CC(C)=CC(C)=C3)ON=C2C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 10 mg/mL (34.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4092 mL | 17.0462 mL | 34.0925 mL | 85.2311 mL |
| 5 mM | 0.6818 mL | 3.4092 mL | 6.8185 mL | 17.0462 mL | |
| 10 mM | 0.3409 mL | 1.7046 mL | 3.4092 mL | 8.5231 mL | |
| 15 mM | 0.2273 mL | 1.1364 mL | 2.2728 mL | 5.6821 mL | |
| 20 mM | 0.1705 mL | 0.8523 mL | 1.7046 mL | 4.2616 mL | |
| 25 mM | 0.1364 mL | 0.6818 mL | 1.3637 mL | 3.4092 mL | |
| 30 mM | 0.1136 mL | 0.5682 mL | 1.1364 mL | 2.8410 mL |
UNC7437 Related Classifications
HY-175476 Related Classifications
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