Zapalog
Based on 1 publication(s) in Google Scholar
Zapalog is a photocleavable small-molecule heterodimerizer that can be used to repeatedly initiate, and instantaneously terminate, a physical interaction between two target proteins. Zapalog dimerizes any two proteins tagged with the FKBP and DHFR domains until exposure to light causes its photolysis.
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- Pureza: 99.62%
- No. CAS: 1708091-24-0
- Fòrmula: C58H73N7O15
- Peso molecular:1108.24
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Zapalog
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Actividad biológica
FKBP, DHFR[1]
Chemical Information
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No. CAS 1708091-24-0
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Appearance Solid
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Peso molecular 1108.24
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Fòrmula C58H73N7O15
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Color White to yellow
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SMILES
O=C([C@H]1N(C(C(C(C)(C)CC)=O)=O)CCCC1)O[C@@H](C2=CC=CC(NC(CCCOC3=CC([N+]([O-])=O)=C(C(OCCOC4=C(OC)C=C(CC5=CN=C(N)N=C5N)C=C4OC)C)C=C3OC)=O)=C2)CCC6=CC=C(OC)C(OC)=C6
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvente y solubilidad
DMSO : 100 mg/mL (90.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.9023 mL | 4.5117 mL | 9.0233 mL | 22.5583 mL |
| 5 mM | 0.1805 mL | 0.9023 mL | 1.8047 mL | 4.5117 mL | |
| 10 mM | 0.0902 mL | 0.4512 mL | 0.9023 mL | 2.2558 mL | |
| 15 mM | 0.0602 mL | 0.3008 mL | 0.6016 mL | 1.5039 mL | |
| 20 mM | 0.0451 mL | 0.2256 mL | 0.4512 mL | 1.1279 mL | |
| 25 mM | 0.0361 mL | 0.1805 mL | 0.3609 mL | 0.9023 mL | |
| 30 mM | 0.0301 mL | 0.1504 mL | 0.3008 mL | 0.7519 mL | |
| 40 mM | 0.0226 mL | 0.1128 mL | 0.2256 mL | 0.5640 mL | |
| 50 mM | 0.0180 mL | 0.0902 mL | 0.1805 mL | 0.4512 mL | |
| 60 mM | 0.0150 mL | 0.0752 mL | 0.1504 mL | 0.3760 mL | |
| 80 mM | 0.0113 mL | 0.0564 mL | 0.1128 mL | 0.2820 mL |
Zapalog Related Classifications
HY-126316 Related Classifications
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