Exatecan Intermediate 4 dihydrochloride

Cat. No.: HY-W021377C Purity: 99.92%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Exatecan Intermediate 4 dihydrochloride is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers.

For research use only. We do not sell to patients.

Exatecan Intermediate 4 dihydrochloride Chemical Structure

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
5 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Other Forms of Exatecan Intermediate 4 dihydrochloride:

Exatecan Intermediate 4 In-stock

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Description

Molecular Weight

281.15

Formula

C₁₁H₁₅Cl₂FN₂O

Appearance

Solid

Color

Brown to breen

SMILES

[H]Cl.[H]Cl.CC1=C2CCC(C(C2=C(C=C1F)N)=O)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 20 mg/mL (71.14 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5568 mL	17.7841 mL	35.5682 mL
5 mM	0.7114 mL	3.5568 mL	7.1136 mL
10 mM	0.3557 mL	1.7784 mL	3.5568 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.92%

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Data Sheet (244 KB) SDS (251 KB)

COA (249 KB) RP-HPLC (219 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5568 mL	17.7841 mL	35.5682 mL	88.9205 mL
	5 mM	0.7114 mL	3.5568 mL	7.1136 mL	17.7841 mL
	10 mM	0.3557 mL	1.7784 mL	3.5568 mL	8.8921 mL
	15 mM	0.2371 mL	1.1856 mL	2.3712 mL	5.9280 mL
	20 mM	0.1778 mL	0.8892 mL	1.7784 mL	4.4460 mL
	25 mM	0.1423 mL	0.7114 mL	1.4227 mL	3.5568 mL
	30 mM	0.1186 mL	0.5928 mL	1.1856 mL	2.9640 mL
	40 mM	0.0889 mL	0.4446 mL	0.8892 mL	2.2230 mL
	50 mM	0.0711 mL	0.3557 mL	0.7114 mL	1.7784 mL
	60 mM	0.0593 mL	0.2964 mL	0.5928 mL	1.4820 mL