1. Protein Tyrosine Kinase/RTK
  2. FLT3
  3. FLT3-IN-4

FLT3-IN-4 

Cat. No.: HY-128571
Handling Instructions

FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia.

For research use only. We do not sell to patients.

FLT3-IN-4 Chemical Structure

FLT3-IN-4 Chemical Structure

CAS No. : 2304799-09-3

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Description

FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].

In Vitro

FLT3-IN-4 (Compound 9u) shows potent inhibitory activities against MV4-11 and Molm-13 cells with IC50 values are 0.089±0.001 nM and 0.022±0.003 nM, respectively[1].

Molecular Weight

431.49

Formula

C₂₃H₂₅N₇O₂

CAS No.

2304799-09-3

SMILES

C=CCN1C2=NC=NC(N)=C2C(C3=CC=C(NC(NC4=NOC(C(C)(C)C)=C4)=O)C=C3)=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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FLT3-IN-4
Cat. No.:
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