1. Anti-infection
  2. HBV
  3. Fosclevudine alafenamide

Fosclevudine alafenamide  (Synonyms: ATI-2173)

Cat. No.: HY-147269
Handling Instructions

Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV.

For research use only. We do not sell to patients.

Fosclevudine alafenamide Chemical Structure

Fosclevudine alafenamide Chemical Structure

CAS No. : 1951476-79-1

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Description

Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1].

IC50 & Target

EC50: 1.71 μM (HBV)[1]

In Vitro

Fosclevudine alafenamide (Compound EIDD-02173) shows cytotoxicity against CEM, A204, IEC-6 and H9c cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: CEM, A204, IEC-6, H9c
Concentration: 0-400 μM
Incubation Time: 6 days
Result: Showed cytotoxicity with CC50 values of 140, 330, 307 and 344 μM against CEM, A204, IEC-6 and H9c cells, respectively.
Molecular Weight

529.45

Formula

C22H29FN3O9P

CAS No.
SMILES

O=C(C(C)=CN1[C@@H]2[C@H](F)[C@@H](O)[C@H](CO[P@@](N[C@@H](C)C(OC(C)C)=O)(OC3=CC=CC=C3)=O)O2)NC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Fosclevudine alafenamide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fosclevudine alafenamide
Cat. No.:
HY-147269
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