FPR-A14 (Standard)
FPR-A14 (Standard) is the analytical standard of FPR-A14 (HY-103472). This product is intended for research and analytical applications. FPR-A14 is a potent formyl peptide receptor (FPR) agonist. FPR-A14 is a potent activator of neutrophil Ca2+ mobilization and chemotaxis with EC50s of 630 nM and 42 nM, respectively. FPR-A14 induces cell differentiation.
For research use only. We do not sell to patients.
- CAS No.: 329691-12-5
- Formula: C23H20N2O5
- Molecular Weight:404.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 329691-12-5
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Molecular Weight 404.42
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Formula C23H20N2O5
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SMILES
O=C(C1=CC=C(OCO2)C2=C1)N/N=C/C3=CC=C(OCC4=CC=CC=C4)C(OC)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Igor A Schepetkin, et al. High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists. Mol Pharmacol. 2007 Apr;71(4):1061-74. [Content Brief]
[2]. Peter J G Cussell, et al. The formyl peptide receptor agonist FPRa14 induces differentiation of Neuro2a mouse neuroblastoma cells into multiple distinct morphologies which can be specifically. inhibited with FPR antagonists and FPR knockdown using siRNA. PLoS One. 2019 Jun 6;14(6):e0217815. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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