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Cat. No.: HY-N9292

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Friedelin-3,4-lactone

Friedelin-3,4-lactone (Compound 4) is a triterpene can be isolated from the leaves of Garcia parViflora with weak antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 29621-75-8
Formula: C₃₀H₅₀O₂
Molecular Weight:442.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Friedelin-3,4-lactone Chemical Structure

CAS No.: 29621-75-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Friedelin-3,4-lactone (Compound 4) is a triterpene can be isolated from the leaves of Garcia parViflora with weak antitumor activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2 2.2.15	CC₅₀	481.7 μM Compound: C2	Cytotoxicity against human HepG2.215 cells assessed as reduction in cell viability after 3 days by MTT assay Cytotoxicity against human HepG2.215 cells assessed as reduction in cell viability after 3 days by MTT assay	[PMID: 29627260]
U-251	IC₅₀	17.1 μM Compound: 4	Cytotoxicity against human U251 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human U251 cells after 48 hrs by sulforhodamine B assay	[PMID: 20958014]

In Vitro

Friedelin-3,4-lactone (Compound 4) is cytotoxic to the U251 cells with an IC₅₀ of 17.1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 29621-75-8
Molecular Weight 442.72
Formula C₃₀H₅₀O₂
SMILES

C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CCC(C)(C3)C)C)(CC[C@@]4([C@]2([H])CC[C@]5([C@@]4([H])CCC(O[C@@H]5C)=O)C)C)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Reyes BM, et al. Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes. J Nat Prod. 2010 Nov 29;73(11):1839-45. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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