G-814 intermediate-1
G-814 intermediate-1 (compound 9) is an intermediate in the synthesis of G-814. G-814 intermediate-1 can be used for the synthesis of ADCs.
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- CAS. Nr.: 1430463-95-8
- Formel: C50H80N4O10Si2
- Molecular Weight:953.36
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Speicherung:Shipping with dry ice
-80°C
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1430463-95-8
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Appearance Solid
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Molecular Weight 953.36
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Formel C50H80N4O10Si2
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SMILES
O=C(N1[C@@H](CC(C1)=C)CO[Si](C)(C)C(C)(C)C)C2=C(C=C(C(OC)=C2)OCCCCCOC3=C(C=C(C(N)=C3)C(N4[C@@H](CC(C4)=C)CO[Si](C)(C)C(C)(C)C)=O)OC)NC(OC(C)(C)C)=O
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Versand
Shipping with dry ice.
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Speicherung
-80°C
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (104.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0489 mL | 5.2446 mL | 10.4892 mL | 26.2230 mL |
| 5 mM | 0.2098 mL | 1.0489 mL | 2.0978 mL | 5.2446 mL | |
| 10 mM | 0.1049 mL | 0.5245 mL | 1.0489 mL | 2.6223 mL | |
| 15 mM | 0.0699 mL | 0.3496 mL | 0.6993 mL | 1.7482 mL | |
| 20 mM | 0.0524 mL | 0.2622 mL | 0.5245 mL | 1.3112 mL | |
| 25 mM | 0.0420 mL | 0.2098 mL | 0.4196 mL | 1.0489 mL | |
| 30 mM | 0.0350 mL | 0.1748 mL | 0.3496 mL | 0.8741 mL | |
| 40 mM | 0.0262 mL | 0.1311 mL | 0.2622 mL | 0.6556 mL | |
| 50 mM | 0.0210 mL | 0.1049 mL | 0.2098 mL | 0.5245 mL | |
| 60 mM | 0.0175 mL | 0.0874 mL | 0.1748 mL | 0.4371 mL | |
| 80 mM | 0.0131 mL | 0.0656 mL | 0.1311 mL | 0.3278 mL | |
| 100 mM | 0.0105 mL | 0.0524 mL | 0.1049 mL | 0.2622 mL |