5-CITEP
5 CITEP is a potent HIV integrase inhibitor; its IC50s by multiple MIA and MPA are 2.3 ± 0.1 μM and 2.1 ± 0.1 μM, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 900779-63-7
- Fòrmula: C12H8ClN5O2
- Peso molecular:289.68
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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- Referencias
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Help & FAQs
Actividad biológica
Chemical Information
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No. CAS 900779-63-7
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Peso molecular 289.68
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Fòrmula C12H8ClN5O2
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SMILES
O=C(C=C(O)C1=NN=NN1)C2=CC=3C=C(Cl)C=CC3N2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Goldgur Y, et al. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13040-3. [Content Brief]
[2]. Johnson AA, et al. Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop. J Biol Chem. 2006 Jan 6;281(1):461-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-CITEP Related Classifications
HY-50693 Related Classifications
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