CGP11952
CGP11952 is a triazolyl-Benzaphenon resembling the benzodiazepines in its pharmacological action. CGP11952 is an experimental benzodiazepine derivative.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 64078-09-7
- Fòrmula: C21H21Cl2N5O2
- Peso molecular:446.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
Benzodiazepine[2]
In Vitro
CGP11952 (CGP 11952) is a triazolyl-Benzaphenon resembling the benzodiazepines in its pharmacological action[1]. The effects of CGP11952 (CGP 11.952), a triazolyl Benzophenone, on cognitive functioning are assessed by means of a computerized neuropsychological battery. In the first study CGP11952 turns out to have a positive effect on information processing speed, perceptual sensitivity and preciseness of responses. Negative effects are found on reaction time. In the second study this latter effect is less clear. A striking result is the less negative effect on memory consolidation under influence of CGP11952 in comparison with other benzodiazepines[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 64078-09-7
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Peso molecular 446.33
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Fòrmula C21H21Cl2N5O2
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SMILES
O=C(C1=NN(C2=CC=C(Cl)C=C2C(C3=CC=CC=C3Cl)=O)C(CN(C)C)=N1)NCC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Van Wieringen A, et al. Electroencephalographic findings in antiepileptic drug trials: a review and report of 6 studies. Epilepsy Res. 1987 Jan;1(1):3-15. [Content Brief]
[2]. Alpherts WC, et al. CGP 11.952: an experimental benzodiazepine derivative. Effects on cognitive functioning in patients with epilepsy. Prog Neuropsychopharmacol Biol Psychiatry. 1987;11(6):673-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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