CDKL
Cyclin-dependent kinase-like family
Cyclin-dependent kinase-like (CDKL) family proteins are serine/threonine protein kinases. Its name is due to the sequence similarity with CDK and it consists of 5 members (CDKL1-5). Their function in protein phosphorylation underpins their important role in cellular activities, including cell cycle, apoptosis, autophagy and microtubule dynamics.
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Productos relacionados con CDKL (1)
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GSK3-IN-10
0 ImagesReferencia número: HY-172198No. CAS: 844441-56-1GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3α and GSK3β with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of β-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress.
