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Referencia número: HY-185977

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a12Dab4

a12Dab4 is a peptide ionizable lipid (PIL) used in lipid nanoparticle (LNP) formulations for targeted delivery of mRNA to the liver.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 3113145-01-7
Fòrmula: C₁₁₄H₂₂₉N₉O₅
Peso molecular:1806.10

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

a12Dab4 Chemical Structure

No. CAS: 3113145-01-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

a12Dab4 is a peptide ionizable lipid (PIL) used in lipid nanoparticle (LNP) formulations for targeted delivery of mRNA to the liver^[1].

In Vivo

a12Dab4 enables organ-specific prime editing in mouse liver through co-delivery of PEmax mRNA and engineered prime editing guide RNAs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 3113145-01-7
Peso molecular 1806.10
Fòrmula C₁₁₄H₂₂₉N₉O₅
SMILES

CC(N[C@H](C(N[C@@H](CCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C(N[C@@H](CCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C(N[C@@H](CCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C(N)=O)=O)=O)=O)CCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Lin Y, et al. Tissue-specific mRNA delivery and prime editing with peptide-ionizable lipid nanoparticles. Nature materials. 2026 Jan;25(1):133-145. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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