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Referencia número: HY-P99276

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Abagovomab

(Synonyms: Anti-Human CA-125 Recombinant Antibody)

1 Cited Publications

Revisión del cliente

Based on 1 publication(s) in Google Scholar

Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a mouse monoclonal anti-idiotypic antibody that targets the tumor-associated antigen CA-125 (binding affinity: 0.5 nM). Produced by mouse hybridoma cells, Abagovomab mimics human TAA, CA-125. Abagovomab also induces humoral and cellular immune responses against ovarian cancer (oc).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: ≥95.0%
No. CAS: 792921-10-9
Peso molecular:144.42 kDa

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Abagovomab Chemical Structure

No. CAS: 792921-10-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Aplicación
Chemical Information
Publications (1)
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target

MUC16

In Vitro

Abagovomab binds the paratope of the OC125 antibody with high affinity (0.5 nM) and functionally mimics the CA-125 antigen, as demonstrated by 93% inhibition of its OC125 binding by native CA-125^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

94025 [NCBI]

Accession

Q8WXI7

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG1-kappa

Aplicación

ELISA, FACS, Functional assay

Chemical Information

No. CAS 792921-10-9
Appearance Liquid
Peso molecular 144.42 kDa
Color Colorless to light yellow
SMILES

[Abagovomab]
Synonyms

Anti-Human CA-125 Recombinant Antibody
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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J Am Chem Soc

A Spatially Controllable DNA Origami-Based T-Cell Cluster Engager for Precise Tumor Elimination. [Abstract]

2026 Jan 21;148(2):2758-2768. PMID: 41504034

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (257 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Referencias

[1]. Grisham RN, et al. Abagovomab: an anti-idiotypic CA-125 targeted immunotherapeutic agent for ovarian cancer. Immunotherapy. 2011;3(2):153-162. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Abagovomab

1 Cited Publications

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Actividad biológica
- Descripciòn
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Aplicación
Chemical Information
Publications (1)
Pureza y Documentación
Referencias

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Referencia número:
Cantidad:
MCE Japan Authorized Agent:

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Abagovomab

Antibody Inhibitor Library

Publications Citing Use of MedChemExpress (MCE) Abagovomab

Actividad biológica

Chemical Information

Publications (1)

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Abagovomab

Cell-ATP Viability Detection Kit

Protein A Agarose

HOLO Human Interleukin-2 (IL-2) Detection Kit

Bradford Protein Assay Kit

PBS Buffer (1×)

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

Antibody Inhibitor Library

Publications Citing Use of MedChemExpress (MCE) Abagovomab

Actividad biológica

Chemical Information

Publications (1)

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Abagovomab Related Classifications

HY-P99276 Related Classifications