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United States

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Referencia número: HY-163077

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Anticancer agent 175

Anticancer agent 175 (complex 1) ia a near-infrared (NIR) luminescent theranostic complex. Anticancer agent 175 induces ROS accumulation, mitochondrial damage, disruption of Bax/Bcl-2 equilibrium, and tumor cell apoptosis in HepG2 cell line.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₈₁H₈₆F₁₀IrN₈O₄P^-
Peso molecular:1648.78

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Anticancer agent 175 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Chemical Information

Peso molecular 1648.78
Fòrmula C₈₁H₈₆F₁₀IrN₈O₄P^-
SMILES

CC1=C2C3=CC=CC=C3[Ir]45([N]6=C7C=C(F)C(F)=CC7=NC(C)=C6C8=CC=CC=C84)([N]9=C%10C=CC=CC%10=C(C(NCCCCCCNC([C@@](C)(CC[C@@]%11(CC[C@@]%12(C%13=CC([C@@]%14([C@]%15(CC[C@@H](C([C@@]%15(CC[C@@]%12%14C)[H])(C)C)O)C)[H])=O)C)C)C[C@]%11%13[H])=O)=O)C=C9C%16=CC=CC=[N]%165)[N]2=C%17C=C(F)C(F)=CC%17=N1.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Wang L, et al. A glycyrrhetinic acid-iridium(III) conjugate as a theranostic NIR probe for hepatocellular carcinoma with mitochondrial-targeting ability. Eur J Med Chem. Published online November 25, 2023. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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